![]() A recent addition to the range is the Jing Real Projects Camera, which is capable of simultaneously recording one up to four projectors the real projects camera is also capable of simultaneously recording four projectors, a DVD player, up to twelve audio channels, and USB ports. In recent years, the company has released versions that can record two, four, six, eight, ten and twelve monitors. A year later, the company introduced a version known as the Jing Card that included a camera with the ability to capture up to eight computer monitors. The earliest model of Jing is the Jupiter-X, a desktop model that did not incorporate a special recording device. The Jing brand was introduced in the nineties, initially for PC video recorders and "digital cameras," and later evolved to include Mac compatible systems. Select either the Mac OS x or PC version. If you see a thumbnail in the corner of your screen, click it to edit the screenshot. Jing is a free software program that allows you to capture screenshot images or. To take the screenshot, release your mouse or trackpad button. Capture an image of what you see on your computer screen with Jing for Mac. Whether for work, home, or play, Jing for macOS gives you the ability to add basic visual elements to your captures and share them fast. To cancel taking the screenshot, press the Esc (Escape) key. Try this app for a free and simple way to start sharing images and short videos of your computer screen. To move the selection, press and hold Space bar while dragging. Eventually, the TechSmith Company released the much improved "Jing Capture Pro" in the eighties, which introduced the first real-time, multitasking computer screen capture system. Drag the crosshair to select the area of the screen to capture. ![]() At first, the Jing concept was not based on a camera, but instead on an electronic paper tape recorder. In the late eighties, the original "jing" computer screen capture system became the TechSmith Jupiter. Though the Mac differs somewhat from the PARC system in many ways, including its use of hardware, it is widely considered the ancestor of the Mac, or at least the first Mac. Jobs based his idea on a Xerox PARC system he worked on as a college student in the early days. With the all-in-one panel, It can capture a photo, save the photo to a. Retired technology enthusiast and computer geek Steve Jobs are often attributed with creating the Mac, the first "intelligent" personal computer. A screenshot is a picture of your screen whether you want to send it to someone. ![]()
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![]() ![]() Open match at Louis Armstrong Stadium on Wednesday night, as rain made its way into the stadium in spite of its roof. The agency defines such emergencies as “exceedingly rare situations when extremely heavy rain is leading to a severe threat to human life and catastrophic damage,” typically with “life-threatening water rises resulting in water rescues/evacuations.”Īt times, strong wind gusts blew the rain sideways, enough to delay a U.S. The flash flood emergency issued by the National Weather Service was more severe than a flash flood watch or even a flash flood warning. In Jamaica, Queens, one person died and another was taken to a hospital after firefighters responded to a report of flooding, the New York Fire Department said in a statement.Īround 9 p.m., the Weather Service issued a tornado warning for parts of the Bronx, after radar indicated a tornado had formed in the area. The authorities were preparing to evacuate residents in part of the city, after the Passaic River breached its banks on Wednesday night and caused significant flooding downtown. In Passaic, at least one person was believed to have died after being trapped in a car in the rising floodwaters, Mayor Hector C. “Passengers are being diverted from ground-level flooded areas.” “All flight activity is currently suspended & travelers are strongly advised to contact their airline for the latest flight & service resumption information,” the statement said. ![]() Newark Airport was experiencing “severe flooding,” the airport said in a statement on Twitter, confirming videos posted on social media that showed deep water pooling inside. The Metropolitan Transportation Authority advised customers in an email alert late Wednesday: “Train service is extremely limited, if not even suspended, because of heavy rainfall and flooding across the region.” The system’s website showed service was suspended across more than 18 subway lines.Īll New Jersey rail service, with the exception of the Atlantic City line, was suspended, New Jersey Transit said.Īt Newark Liberty International Airport, 3.24 inches of rain were recorded between 8 and 9 p.m., the Weather Service said. A road through Central Park was dotted with cars that had been abandoned after getting stuck in the floodwaters. “All non-emergency vehicles must be off NYC streets and highways,” the emergency management office said on Twitter. Just before 1 a.m., the city issued a travel ban in effect until 5 a.m. Mayor Bill de Blasio declared a state of emergency just before 11:30 p.m., saying New York City was “enduring a historic weather event” with “record breaking rain across the city, brutal flooding and dangerous conditions on our roads.” He warned New Yorkers: “Stay inside.” The National Weather Service issued a flash flood emergency in New York City for the first time.Īt least two deaths were reported in the flooding, one in Queens and one in Passaic, N.J. The rain on Wednesday night - 3.1 inches in Central Park within an hour - shattered the record set only last week, when 1.94 inches of rain fell in the park during Tropical Storm Henri. ![]() Open in Queens when the rain came into the roofed stadium sideways. The remnants of Hurricane Ida barreled into the New York City region on Wednesday evening with furious, wind-driven rain that all but halted subway service, splintered homes in New Jersey, raised a tornado warning for the Bronx, and delayed the U.S. ![]() Go here for the latest on deadly flooding in New York. The remnants of Hurricane Ida continued to advance through the Mid-Atlantic toward southern New England, creating at least one tornado and hazardous flooding conditions in the region. ![]() ![]() ![]() Try Using Another Virtual Camera Software – FineCam Your OBS virtual camera not showing up should now be fixed! Tip 7. So, before you restart your PC, try to temporarily disable your firewall, then close the OBS Studio and restart your PC. It’s not necessarily that the method will work, but it’s an excellent first move of fixing the OBS camera not showing up.įurthermore, if your OBS Studio is not loading any feeds, your firewall or antivirus is likely blocking it. Most problems only require restarting the running services, and when it reboots and starts afresh, everything works fine. Restart OBS Studio and Your Computer.Īs a rule of thumb, restarting the OBS Studio and your computer is a quick way to fix errors. That’s it! Discord should now detect your OBS camera. sudo codesign –remove-signature “/Applications/Discord.app/Contents/Frameworks/Discord Helper (plugin).app”.sudo codesign –remove-signature “/Applications/Discord.app/Contents/Frameworks/Discord Helper (GPU).app”.sudo codesign –remove-signature “/Applications/Discord.app/Contents/Frameworks/Discord Helper.app”.If that doesn’t work, try the commands below one after the other, checking if they work. After step 3, your OBS virtual camera should start after restarting your Mac. sudo codesign –sign – “/Applications/Discord.app/Contents/Frameworks/Discord Helper (Renderer).app”.sudo codesign –remove-signature “/Applications/Discord.app/Contents/Frameworks/Discord Helper (Renderer).app”.Next, on the terminal, enter the command below Do so even if it won’t display as you enter it on the screen. You will get a prompt to enter your password. Open your Terminal app and enter the following: If this is your case, try the steps below. If you are using a Mac, you might notice that there is no option for OBS Virtual Camera on Discord. ![]() I hope your camera not working error is now fixed. If you need to switch between the apps, disable the camera in one app and open it in another. The camera will start working either in webcam view or whichever layout you are using.įor this tip, the point is that anytime you are using OBS, always ensure only one app is using it at a time.
![]() ![]() All of these headphones use similar Foster biodynamic drivers, but obviously the tuning varies. They seem to be preferred by nearly everyone who has tried them internal to AQ and external. The Nightowl is a little cleaner, so that might be a decent option. New pads : I'm trying to get those out as soon as possible! Ideally before the holidays. We might (BIG might) do other colors/finishes in the future. The headphone stand is black so that it will match anything. But they are just different enough that I believe it is worth listening to both before deciding if you want one or the other. The goal was for them to be as close as possible. The cables conductors are made of high-purity copper drawn and. ![]() NightOwl Carbon benefits from that experience, extending to a durable cable designed to effectively control noise and minimize distortion, thus enabling a deeper emotional connection between listener and music. NightHawk and NightOwl sound very similar. AudioQuest has designed and refined high-performance cables since 1980. I bought them when they were just released, at around 700-ish euro. If you are thinking about buying a NightHawk, I suggest waiting until after our announcements next week. Ive been using a pair of AudioQuest Nightowl Carbon headphones for a few years now. The earcups are still made the same way from liquid wood. In our cable lineup, we reserve "Carbon" for digital cables only. We call the new headphones "Carbon" because of the finish, not because of the cable. We buy the same paint Porsche uses on the Panamera called "Carbon Gray Metallic." It's a near-black shade with a subtle hint of golden warmth. Closed Design: The NightOwl Carbon is a true closed-back headphone to give you maximum isolation from the outside world. The new finish is an automotive-inspired process that consists of multiple layers of primer, base coats, and clear coats-all automated with a final hand-polish for quality control. The new Carbon finishes most definitely cost more to produce versus the four clear coats on the current NightHawks. If I can get the sound I am after for less than half the price of the IEMs I am looking at, then that is certainly something worth considering.Update from AudioQuest (More info on Nov 1.) This is mainly a question about whether or not I should consider headphones now that this hobby is starting to escalate a bit. Filed Under: Closed-back headphones, Headphone Reviews, Over-ear headphones Tagged With: Audioquest Nighthawk, audioquest nightowl review, nightowl headphone. My main question about the Nightowl is how well are instruments reproduced? Primarily for classical music, where much of the emotion of a piece is presented by using certain instruments at specific times.Īlso, how well should I expect the Nightowl to perform compared to TOTL IEMs? Headphones have an obvious advantage, but I have no idea how big that difference is these days. After having read various reviews and looked at a number of headphones, it seems to me that perhaps the Nightowl might have the sort of signature I prefer. I know what I would like in IEMs, but for headphones I am pretty much at a loss. I am looking around to find a smooth and organic sound that has very realistic timbre. I would like to get a sense of headphone performance compared to IEMs and in particular the Nightowl relative to TOTL IEMs. So bear with me for a bit, as I am quite the headphone noob and more at home with IEMs. ![]() ![]() ![]() I have created a custom overlay for RTSS. 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Welcome to /r/AMD - the subreddit for all things AMD come talk about Ryzen, Radeon, Threadripper, EPYC, rumors, reviews, news and more. Latest PC build question and Tech Support Megathread r/AMD Discord Official AMD Discord FILTER BY: NEWS REVIEW RUMOR PHOTO Latest Drivers & Tech Support ![]() ![]() ![]() We are excited to announce that starting today we are releasing new versions of many of our Microsoft 365 for Mac apps that run natively on Macs with M1. Word, Excel, PowerPoint, and OneNote: Select the Send a Smile icon in the top-right corner of the app.Universal app support for Macs with M1 is here If you encounter any issues while using Office, please send us feedback so we can address them. See About Office: What version of Office am I using? Send feedback for Office for Mac You can download the latest Office for Mac suite installer. Word, Excel, PowerPoint, Outlook, and OneNote will run on OS X 10.10 Yosemite and later.įor the best experience with macOS Catalina 10.15, be sure to keep your Office apps up-to-date. Learn what Office 2016 for Mac end of support means for you ![]() However, you won't receive any more software updates, including security updates for Office for Mac 2016. All your Office 2016 apps will continue to function-they won't disappear from your Mac, nor will you lose any data. Important: Support for Office 2016 for Mac ended October 13, 2020. Yes. For the best experience with the new operating system, make sure that you have installed the latest updates for Word, Excel, PowerPoint, Outlook and OneNote. If you continue with an older version of macOS, your Office apps will still work, but you'll no longer receive any updates including security updates. Starting with the November 2022 update (16.67) macOS Big Sur 11 or later is required to receive updates to Word, Excel, PowerPoint, Outlook, and OneNote. We recommend that you upgrade to Microsoft 365 for Mac or Office 2021 for Mac. Important: Support for Office 2019 for Mac will end on October 10th, 2023. Starting with the November 2022 update (16.67) macOS Big Sur 11 or later is required to receive updates to Word, Excel, PowerPoint, Outlook and OneNote. ![]() OneDrive: Select Send Feedback from the Help & Settings tab. Outlook: Select Contact Support from the Help menu. Word, Excel, PowerPoint and OneNote: Select the Feedback icon in the top-right corner of the app. For the best experience with the new operating system, make sure that you have installed the latest updates for Word, Excel, PowerPoint, Outlook and OneNote. For example, if you’re on macOS Big Sur 11, but later you don’t update your macOS to a supported version when macOS Big Sur 11 is no longer supported, you won’t receive any updates of any kind.Īs new major versions of macOS are released and older versions become unsupported, we highly recommend you continue to update your macOS to a supported version in order to receive mainstream support such as security updates as well as new features. ![]() If you’re on an unsupported version of macOS, your Office apps will still work but you would no longer receive any updates including security updates. What if I don't update macOS to a supported version? Learn more about the latest macOS releases. The October 2022 update (16.66) is the last build to support macOS Catalina 10.15. Note that new installs of Microsoft 365 for Mac also requires macOS Big Sur 11 or later. Upgrading your operating system to macOS Big Sur 11 or later will allow Office updates to be delivered for your apps. Starting with the November 2022 update (16.67) macOS Big Sur 11 or later is required to receive updates to Word, Excel, PowerPoint, Outlook, OneNote, and Microsoft Defender. ![]() ![]() ![]() The trial’s prespecified dual primary outcomes were major adverse CV event (MACE) (the composite of CV death, myocardial infarction, or ischemic stroke) demonstrating noninferiority for dapagliflozin versus placebo, and the composite of CV death or hospitalization for heart failure, which achieved superiority of dapagliflozin over placebo. Patients were followed for a median of 4.2 years (interquartile range 3.9–4.4). Patients were randomly assigned in a double-blinded fashion to receive dapagliflozin 10 mg/day or matching placebo (1:1), on top of standard-of-care therapy for other comorbidities. At screening, eligible patients had HbA 1c 6.5–12% and CrCl (estimated by the Cockcroft-Gault equation) ( 16) ≥60 mL/min. The DECLARE-TIMI 58 trial enrolled 17,160 patients with T2D and either established atherosclerotic CV disease (ASCVD age ≥40 years and ischemic heart disease, cerebrovascular disease, or peripheral arterial disease 40.6%), or patients with multiple risk factors for ASCVD (≥60 years for women or ≥55 years for men plus one or more of the following: dyslipidemia, hypertension, or current tobacco use 59.4%) ( 15). Here, using data from DECLARE-TIMI 58, we analyzed the rate of kidney function loss and eGFR slopes for participants randomized to dapagliflozin versus placebo, focusing on subpopulations with low baseline kidney risk. This trial specifically enrolled patients with creatinine clearance (CrCl) ≥60 mL/min, most of them (69.1%) within the normoalbuminuric range ( 14). Compared with these other randomized controlled trials, the DECLARE-TIMI 58 trial included the largest population of patients with T2D and the longest follow-up period. SGLT2i kidney protection was further proven in patients with albuminuric CKD with or without T2D (Dapagliflozin And Prevention of Adverse outcomes in Chronic Kidney Disease ) ( 13). In patients with T2D, the protective effects of sodium–glucose cotransporter 2 inhibitors (SGLT2i) on kidney function have been demonstrated either as the primary outcome (Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation trial) in patients with albuminuric diabetic kidney disease or as a secondary or exploratory analysis of cardiovascular (CV) outcome trials (CVOTs Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients-Removing Excess Glucose, Canagliflozin Cardiovascular Assessment Study program, Dapagliflozin Effect on Cardiovascular Events–Thrombolysis in Myocardial Infarction 58, Evaluation of Ertugliflozin Efficacy and Safety Cardiovascular Outcomes, and Effect of Sotagliflozin on Cardiovascular and Renal Events in Patients With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk ) ( 6– 12). ![]() ![]() Game and want to purchase it, you can support the developers by doing so here. This download is completely free and won't cost you a penny. Then, launch the game through the desktop shortcut. Double click inside the Fran Bow v1.0.1_unity folder and run the setup application.zip file and click on “Extract to Fran Bow v1.0.1_unity.zip” (To do this you will need 7-Zip, which you can get here, or you can use the built in windows extractor). ![]() Once the game is finished downloading, right click the.Download for free Send to friends at WhatsApp, Facebook. 80 pieces of animated images of curtsies, nods and bows in GIF format. That’s why you’ll need the GIF bows that you’ll find on this page. This is a universal gesture, which is used in a variety of situations. (You can use FDM which is free here, or any other download manager). Bowing is a way to greet a person, to express your gratitude or to say goodbye. We recommend using a download manager for faster download speeds. Wait 5 seconds and click on the blue ‘download now’ button.Click the Download button below and you will be redirected to UploadHaven.After having a dream about her beloved cat, Fran decides to escape from the mental institution to find him and go back home to Aunt Grace, her only living relative. In the forest, Fran goes into shock over the loss of her parents and when she recovers, she’s at Oswald Asylum, an oppressive mental institution for children, and Mr. Midnight, a black cat that Fran had previously received as a present from her parents. After witnessing the gruesome and mysterious loss of her parents, found dismembered at their home, Fran rushes into the woods, together with her only friend, Mr. 50+ interactive unique characters with unique personalities.Fran Bow is a creepy adventure game that tells the story of Fran, a young girl struggling with a mental disorder and an unfair destiny.Interactive and occasionally playable pet cat, Mr Midnight.Three arcade inspired mini-games all with different art style to be part of the transitions in the story.A big variety of puzzles designed with different levels of difficulty and specifically based on the story.Self administer medication to open the terrible hidden world that will help solve puzzles and find objects.Unique and peculiar hand drawn 2D Art-Style and 2D animation.Story driven creepy psychological horror adventure game.After having a dream about her beloved cat, Fran decides to escape from the mental institution to find him and go back home to Aunt Grace, her only living relative. Share a GIF and browse these related GIF searches. ![]() Midnight and shortly after this her Aunt Grace arrives for dinner. ![]() They give her a black cat which she then names Mr. In the forest, Fran goes into shock over the loss of her parents and when she recovers, she’s at Oswald Asylum, an oppressive mental institution for children, and Mr. Upload, customize and create the best GIFs with our free GIF animator See it. 8 References History At the beginning of the game, we see Fran Bow living a happy life with her mother and father as an ordinary little girl. Fran Bow is now available for purchase on Xbox, Playstation, and Nintendo Switch. Midnight, a black cat that Fran had previously received as a present from her parents. Fran Bow on consoles By killmonday Hello sweeties We are happy to announce that the Fran Bow port for consoles is finally ready It has been a long journey with a lot of sweat and tears, and now it has finally reached the end. Fran Bow is a creepy adventure game that tells the story of Fran, a young girl struggling with a mental disorder and an unfair destiny. ![]() ![]() ![]() He lamented how “destructive” Criminal Minds had been for his soul and how concerned he was about the effect it had on audiences.īut the show, defined not by its terrifying look into the criminal psyche but instead by the found-family aspect of the series, managed to endure and gain a devoted following. Mandy Patinkin, who led the team in the first two seasons and abruptly left over “creative differences” at the beginning of the third season, shared his concerns about the darkness of the show in a New York Magazine profile published five years after his departure. The grim nature of the show did not go unnoticed, including by cast members, and the series was characterized by several major actor shake-ups. ![]() Each week introduced a fresh serial killer and an alarmingly creative new way for humans to hurt each other. This was the very nature of the show, which followed the members of the FBI’s Behavioral Analysis Unit as they tracked down the country’s most disturbing unknown subjects (“unsubs”). The CBS series was the most psychologically gruesome of its early-to-mid-aughts procedural counterparts, at times even surpassing SVU in the kinds of disturbing crimes it featured. That’s not a criticism - it was the initial appeal. However, these casting changes had a clear effect on the quality of the season, and the loss of Cook and Brewster posed a nearly insurmountable challenge for the show's writers to overcome.One thing was clear when Criminal Minds premiered in 2005: The show was horrific. It's an exciting plotline made all the more interesting when we learn that JJ knew the whole time that Prentiss was still alive, and we're glad Prentiss was able to come back the following season. At the end of Season 6, Prentiss fakes her death to escape Ian Doyle. ![]() Thankfully, some interesting arcs help prop these episodes up. The idea that "Criminal Minds" could replace JJ with another woman was the biggest mistake of the season, and it was a decision that continued to reverberate for many seasons. Fans were not happy with this replacement, however, and Nichols was let go after only one season. Sure enough, producers brought on newcomer Ashley Seaver (Rachel Nichols) to replace JJ. It's not a bad way to do a finale, but it does make one wonder what the season would have been like had CBS ordered more than 15 episodes.īrewster told the AV Club that she felt they were fired because executives wanted new women on the series to keep it fresh. ![]() Interestingly enough, Season 14 actually ends on a rather joyful note, with Rossi (Joe Mantegna) remarrying his ex-wife Krystall (Gail O'Grady). The problem with this season is mainly that you can tell why the show is doing this, rather than it feeling like a natural progression of the story. It makes sense for a show with over a dozen seasons under its belt to start looking backward, and these episodes aren't unwelcome in a series that can sometimes breeze past all of the terrible things the agents have endured. One mid-season episode also delves into Emily's past with a case related to one they worked on many years ago, leading to, once again, even more flashbacks. We also learn more about some of our team members, especially JJ, who, in one of the best episodes of the season, revisits the trauma of her sister's suicide while working on a case. The season begins with Garcia once again traumatized (it's no wonder she left the BAU in Season 15) in the wake of a kidnapping. ![]() ![]() ![]() (2014) Genome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes. Oksenberg N, Haliburton GD, Eckalbar WL, Oren I, Nishizaki S, Murphy K, Pollard KS, Birnbaum RY, Ahituv N. (2014) Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation. We anticipated that these novel datasets of neuronal enhancers that are involved in the spatiotemporal regulation of IS-associated genes will highlight novel genomic regions that could be involved in epilepsy pathogenesis and brain development.īirnbaum RY, Patwardhan RP, Kim MJ, Findlay G, Smith RP, Zhao J, Ku AA, Shendure J, Ahituv N. Furthermore, enhancer candidates will be tested for their forebrain activity using zebrafish transgenic assays. Using chromatin interaction analysis followed by pair end tag sequencing (ChIA-PET) on the mouse E16.5 forebrain, we hope to reveal the chromatin connectivity between candidate enhancers and promoter regions of IS-associated genes, such as FOXG1 and STXBP1. In this project, not only will the potential regulatory elements be identified but so will their targeted gene promoters. Using advanced sequencing technologies, the regulatory elements of mouse forebrain at embryonic day 16.5 will be explored in order to understand the regulatory networks that are associated with IS. To test this hypothesis, we are focusing on infantile spasms (IS), a sub-type of epilepsy that begins in infancy and is associated with ventral forebrain development and forebrain synapse function. A major and under-explored cause of complex disorders, such as epilepsy, could be mutations in gene regulatory elements, such as enhancers. Epilepsy is a complex and heterogeneous disease, making it difficult to precisely diagnose and provide effective treatments. Functional genomic characterization of gene regulatory elements associated with epilepsy. Using massively parallel reporter assays, we are dissecting the enhancer activity of eExons at single nucleotide resolution to elucidate the effect of mutations on protein function, enhancer activity, or both. However, the functional consequence of point mutations in eExons has yet to be determined. In addition, it was shown that eExons can regulate the gene in which they reside, as well as nearby genes, suggesting that mutations in these exons could lead to phenotypes that are not due to the function of the encoded protein. Furthermore, functional characterization of potential eExons in zebrafish and mice found that over half of them are functional developmental enhancers. Our study analyzing enhancer-associated ChIP-seq datasets (p300, H3K27ac, H3K4me1) found that, on average, 6% of peaks overlap coding exons, suggesting that numerous exonic-enhancers (eExons) are embedded in mammalian genomes. Current Projects The dual function of DNA sequences: coding exons can also function as transcriptional enhancers: Protein coding sequences have been shown to contain additional functional information, such as splicing, mRNA stability, microRNA target sites, and transcriptional enhancer activity. Elucidating gene regulatory elements and their networks are essential to understanding their mechanism of action and the ‘regulatory code’, topics our lab is working to address. Furthermore, mutations in these regulatory elements altering spatiotemporal gene expression can lead to morphological differences between species, developmental abnormalities, and human disease. While many potential regulatory elements have been systemically identified, their targeted genes and tissue-specific activity have yet to be explored. Gene expression is regulated through the integrated action of many distal-regulatory elements, such as enhancers. Proper embryo development requires a precise and carefully orchestrated set of programs that depend on gene expression. “Evolutionary changes in anatomy and way of life are more often based on changes in the mechanisms controlling the expression of genes than on sequence changes in proteins” (Mary-Claire King and A. ![]() |
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